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Exposure to air pollution and tobacco smoking and their combined effects on depression in six low- and middle-income countries

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dc.date.accessioned 2017-10-23 en
dc.date.accessioned 2018-03-08T13:22:28Z
dc.date.available 2018-03-08T13:22:28Z
dc.date.issued 2017-10-23 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/11301
dc.description.abstract Little is known about the joint mental health effects of air pollution and tobacco smoking in low- and middle-income countries. The aim was to investigate the effects of exposure to ambient fine particulate matter pollution (PM2.5) and smoking and their combined (interactive) effects on depression.Multilevel logistic regression analysis of baseline data of a prospective cohort study (n = 41 785). The 3-year average concentrations of PM2.5 were estimated using US National Aeronautics and Space Administration satellite data, and depression was diagnosed using a standardised questionnaire. Three-level logistic regression models were applied to examine the associations with depression.The odds ratio (OR) for depression was 1.09 (95% C11.01-1.17) per 10 ??g/m3 increase in ambient PM2.5, and the association remained after adjusting for potential confounding factors (adjusted OR = 1.10, 95% CI 1.02-1.19). Tobacco smoking (smoking status, frequency, duration and amount) was also significantly associated with depression. There appeared to be a synergistic interaction between ambient PM2.5 and smoking on depression in the additive model, but the interaction was not statistically significant in the multiplicative model.The study suggests that exposure to ambient PM2.5 may increase the risk of depression, and smoking may enhance this effect. en
dc.format.medium Print en
dc.subject POLLUTION en
dc.subject SMOKING en
dc.subject DEVELOPING COUNTRIES en
dc.subject DEPRESSION en
dc.title Exposure to air pollution and tobacco smoking and their combined effects on depression in six low- and middle-income countries en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber ZPAEAR en
dc.Volume 211(3) en
dc.BudgetYear 2017/18 en
dc.ResearchGroup Population Health, Health Systems and Innovation en
dc.SourceTitle British Journal of Psychiatry en
dc.ArchiveNumber 10039 en
dc.PageNumber 157-162 en
dc.outputnumber 8960 en
dc.bibliographictitle Lin, H., Guo, Y., Kowal, P., Airhihenbuwa, C.O., Di, Q., Zheng, Y., Zhao, X., Vaughn, M.G., Howard, S., Schootman, M., Salinas-Rodriquez, A., Yawson, A.E., Arokiasamy, P., Manrique-Espinoza, B.S., Biritwun, R.B., Rule, S.P., Minicuci, N., Naidoo, N., Chatterji, S., Qian, Z.M., Ma, W. & Wu, F. (2017) Exposure to air pollution and tobacco smoking and their combined effects on depression in six low- and middle-income countries. <i>British Journal of Psychiatry</i>. 211(3):157-162. en
dc.publicationyear 2017 en
dc.contributor.author1 Lin, H. en
dc.contributor.author2 Guo, Y. en
dc.contributor.author3 Kowal, P. en
dc.contributor.author4 Airhihenbuwa, C.O. en
dc.contributor.author5 Di, Q. en
dc.contributor.author6 Zheng, Y. en
dc.contributor.author7 Zhao, X. en
dc.contributor.author8 Vaughn, M.G. en
dc.contributor.author9 Howard, S. en
dc.contributor.author10 Schootman, M. en
dc.contributor.author11 Salinas-Rodriquez, A. en
dc.contributor.author12 Yawson, A.E. en
dc.contributor.author13 Arokiasamy, P. en
dc.contributor.author14 Manrique-Espinoza, B.S. en
dc.contributor.author15 Biritwun, R.B. en
dc.contributor.author16 Rule, SP en
dc.contributor.author17 Minicuci, N. en
dc.contributor.author18 Naidoo, N. en
dc.contributor.author19 Chatterji, S. en
dc.contributor.author20 Qian, Z.M. en
dc.contributor.author21 Wu, F. en
dc.contributor.author22 Ma, W. en


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