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The effect of male involvement and a prevention of mother-to-child transmission (PMTCT) intervention on depressive symptoms in perinatal HIV-infected rural South African women

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dc.date.accessioned 2019-08-19T12:33:27Z
dc.date.available 2019-08-19T12:33:27Z
dc.date.issued 2019-03-26 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/13637
dc.description.abstract This study investigated perinatal depressive symptoms among HIV-infected women enrolled in a cluster-randomized, controlled trial in South Africa. Women (n = 1370) attending 12 community health centers were consecutively enrolled in a two-phase (phase 1 = without a male partner, phase 2 = with a male partner) and two-condition (experimental or control) prevention of mother-to-child transmission (PMTCT) intervention. Women were enrolled at 8-24 weeks pregnant and followed postpartum at 6 weeks and 6 and 12 months (retention rate = 69.8%). Antenatally, 45.4% of women were above the 12-point Edinburgh Postnatal Depression Scale (EPDS) cutoff, 30.2% were above the cutoff at 6 weeks, and 34.2% and 36.9% at 6 months and 12 months postpartum, respectively. In multilevel regression analyses, depressive symptoms decreased over time among women in phase 2 participating in the intervention condition, but neither condition nor phase alone was associated with a decrease in depression. Greater HIV stigma, increased psychological intimate partner violence, less male involvement, lower education, and non-adherence during pregnancy were associated with increased depressive symptoms over the perinatal period. Results indicated that women participating had high levels of depressive symptoms (> 40% prenatally and > 30% postnatally), and the combination of the multi-session PMTCT intervention plus male partner participation contributed to a reduction in depressive symptoms. Results suggest that interventions targeting the reduction of depressive symptoms in perinatal HIV-positive women by increasing male involvement and decreasing HIV stigma and intimate partner violence are needed to reduce depression in this vulnerable population. en
dc.format.medium Print en
dc.subject WOMEN en
dc.subject HIV/AIDS en
dc.subject DEPRESSION en
dc.subject PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) PROGRAMME en
dc.title The effect of male involvement and a prevention of mother-to-child transmission (PMTCT) intervention on depressive symptoms in perinatal HIV-infected rural South African women en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume February en
dc.BudgetYear 2018/19 en
dc.ResearchGroup HIV/AIDS, STIs and TB en
dc.SourceTitle Archives of Women's Mental Health en
dc.ArchiveNumber 10779 en
dc.PageNumber Online en
dc.outputnumber 9825 en
dc.bibliographictitle Peltzer, K., Abbamonte, J.M., Mandell, L.N., Rodriquez, V.J., Lee, T.K., Weiss, S.M., Jones, D.L. & Jones, D.L. (2019) The effect of male involvement and a prevention of mother-to-child transmission (PMTCT) intervention on depressive symptoms in perinatal HIV-infected rural South African women. <i>Archives of Women's Mental Health</i>. February:Online. en
dc.publicationyear 2019 en
dc.contributor.author1 Peltzer, K. en
dc.contributor.author2 Abbamonte, J.M. en
dc.contributor.author3 Mandell, L.N. en
dc.contributor.author4 Rodriquez, V.J. en
dc.contributor.author5 Lee, T.K. en
dc.contributor.author6 Weiss, S.M. en
dc.contributor.author7 Jones, D.L. en
dc.contributor.author8 Jones, D.L. en


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