FluoroType MTB system for the detection of pulmonary tuberculosis

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dc.date.accessioned	2018-04-06	en
dc.date.accessioned	2022-08-17T14:23:56Z
dc.date.available	2022-08-17T14:23:56Z
dc.date.issued	2018-04-06	en
dc.identifier.uri	http://hdl.handle.net/20.500.11910/12050
dc.description.abstract	FluoroType MTB (Hain Lifescience, Germany) is a new molecular test for the detection of TB that involves DNA amplification and detection via PCR in a closed system, with automated analysis, which can process up to 96 samples within 3 h. The extracted DNA can be used in genotypic DST line probe assays. DNA extraction can be performed manually or using an automated DNA extraction system (GenoXtract). A prospective assessment of the system in a low-incidence setting found the sensitivity and specificity to be 88.1% and 98.9%, respectively, in comparison with culture [4]. However, the system has not been evaluated in resource-poor settings. We sought to evaluate the FluoroType MTB assay in Zankli Research Laboratory, Zankli Medical Centre, Abuja, Nigeria.	en
dc.format.medium	Print	en
dc.subject	TUBERCULOSIS	en
dc.title	FluoroType MTB system for the detection of pulmonary tuberculosis	en
dc.type	Journal Article	en
dc.description.version	Y	en
dc.ProjectNumber	N/A	en
dc.Volume	3(2)	en
dc.BudgetYear	2017/18	en
dc.ResearchGroup	HIV/AIDS, STIs and TB	en
dc.SourceTitle	ERJ Open Research	en
dc.ArchiveNumber	10317	en
dc.URL	http://ktree.hsrc.ac.za/doc_read_all.php?docid=19876	en
dc.PageNumber	Online	en
dc.outputnumber	9281	en
dc.bibliographictitle	Obasanya, J., Lawson, L., Edwards, T., Oladimeji, O., Madukaji, L., Dacombe, R., Dominguez, J., Molina-Moya, B., Adams, E.R. & Cuevas, L.E. (2017) FluoroType MTB system for the detection of pulmonary tuberculosis. ERJ Open Research. 3(2):Online. http://hdl.handle.net/20.500.11910/12050	en
dc.publicationyear	2017	en
dc.contributor.author1	Obasanya, J.	en
dc.contributor.author2	Lawson, L.	en
dc.contributor.author3	Edwards, T.	en
dc.contributor.author4	Oladimeji, O.	en
dc.contributor.author5	Madukaji, L.	en
dc.contributor.author6	Dacombe, R.	en
dc.contributor.author7	Dominguez, J.	en
dc.contributor.author8	Molina-Moya, B.	en
dc.contributor.author9	Adams, E.R.	en
dc.contributor.author10	Cuevas, L.E.	en