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Adolescent barriers to HIV prevention research: are parental consent requirements the biggest obstacle?

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dc.date.accessioned 2020-09-29T08:15:26Z
dc.date.available 2020-09-29T08:15:26Z
dc.date.issued 2020-09-20 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/15438
dc.description.abstract One third of people newly living with HIV/AIDS are adolescents. Research on adolescent HIV prevention is critical owing to differences between adolescents and adults. Parental permission requirements are often considered a barrier to adolescent enrollment in research, but whether adolescents view this barrier as the most important one is unclear. Adolescents were approached in schools in KwaZulu-Natal, South Africa, and at a sexually transmitted infection clinic at the Childrens Hospital of Aurora, Colorado. Surveys with a hypothetical vignette about participation in a pre-exposure prophylaxis trial were conducted on smartphones or tablets with 75 adolescents at each site. We calculated descriptive statistics for all variables, using 2-sample tests for equality of proportions with continuity correction. Statistical significance was calculated at p < 0.05. Multivariate analyses were also conducted. Most adolescents thought side effects (77%) and parental consent requirements (69%) were very important barriers to research participation. When asked to rank barriers, adolescents did not agree on a single barrier as most important, but the largest group of adolescents ranked parental consent requirements as most important (29.5%). Parental consent was seen as more of a barrier for adolescents in South Africa than in the United States. Concerns about being experimented on or researchers mandatory reporting to authorities were ranked much lower. Finally, most (71%, n 106) adolescents said they would want to extra support from another adult if parental permission was not required. Adolescents consider both parental permission requirements and side effects important barriers to their enrollment in HIV prevention research. Legal reform and better communication strategies may help address these barriers. en
dc.format.medium Print en
dc.subject ADOLESCENTS en
dc.subject HIV/AIDS PREVENTION en
dc.subject PARENTAL GUIDANCE en
dc.subject RESEARCH en
dc.subject PARENTAL CONSENT en
dc.title Adolescent barriers to HIV prevention research: are parental consent requirements the biggest obstacle? en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume April en
dc.BudgetYear 1995/96 en
dc.SourceTitle Journal of Adolescent Health en
dc.ArchiveNumber 11527 en
dc.PageNumber Online en
dc.outputnumber 10711 en
dc.bibliographictitle Shah, S.K., Essack, Z., Byron, K., Slack, C., Reirden, D., Van Rooyen, H., Jones, N.R. & Wendler, D.S. (2020) Adolescent barriers to HIV prevention research: are parental consent requirements the biggest obstacle?. <i>Journal of Adolescent Health</i>. April:Online. en
dc.publicationyear 2020 en
dc.contributor.author1 Shah, S.K. en
dc.contributor.author2 Essack, Z. en
dc.contributor.author3 Byron, K. en
dc.contributor.author4 Slack, C. en
dc.contributor.author5 Reirden, D. en
dc.contributor.author6 Van Rooyen, H. en
dc.contributor.author7 Jones, N.R. en
dc.contributor.author8 Wendler, D.S. en


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