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Correlating WHO COVID-19 interim guideline 2020.5 and testing capacity, accuracy, and logistical challenges in Africa

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dc.date.accessioned 2021-08-26T13:15:29Z
dc.date.available 2021-08-26T13:15:29Z
dc.date.issued 2021-08-26 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/16379
dc.description.abstract Coronavirus disease 2019 (COVID-19), a severe acute respiratory syndrome caused by SARS-CoV-2 was declared a global pandemic by the World Health Organization (WHO) in March 2020. As of 21st April 2021, the disease had affected more than 143 million people with more than 3 million deaths worldwide. Urgent effective strategies are required to control the scourge of the pandemic. Rapid sample collection and effective testing of appropriate specimens from patients meeting the suspect case definition for COVID-19 is a priority for clinical management and outbreak control. The WHO recommends that suspected cases be screened for SARS-CoV-2 virus with nucleic acid amplification tests such as real-time Reverse Transcription-Polymerase Chain Reaction (rRTPCR). Other COVID-19 screening techniques such as serological and antigen tests have been developed and are currently being used for testing at ports of entry and for general surveillance of population exposure in some countries. However, there are limited testing options, equipment, and trained personnel in many African countries. Previously, positive patients have been screened more than twice to determine viral clearance prior to discharge after treatment. In a new policy directive, the WHO now recommends direct discharge after treatment of all positive cases without repeated testing. In this review, we discuss COVID-19 testing capacity, various diagnostic methods, test accuracy, as well as logistical challenges in Africa with respect to the WHO early discharge policy. en
dc.format.medium Print en
dc.publisher Earthscan en
dc.subject WORLD HEALTH ORGANISATION (WHO) en
dc.subject COVID-19 en
dc.subject AFRICA en
dc.title Correlating WHO COVID-19 interim guideline 2020.5 and testing capacity, accuracy, and logistical challenges in Africa en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber PSALAA en
dc.Volume 39(89) en
dc.BudgetYear 2021/22 en
dc.ResearchGroup Human and Social Capabilities en
dc.SourceTitle PanAfrican Medical Journal en
dc.ArchiveNumber 12096 en
dc.URL http://ktree.hsrc.ac.za/doc_read_all.php?docid=24514 en
dc.PageNumber Online en
dc.outputnumber 11248 en
dc.bibliographictitle Mosi, L., Sylverken, A.A., Oyebola, K., Badu, K., Dukhi, N., Goonoo, N., Mante, P.K., Zahouli, J., Amankwaa, E.F., Tolba, M.F., Fagbamigbe, A.F., De Souza, D.K. & Matoke-Muhia, D. (2021) Correlating WHO COVID-19 interim guideline 2020.5 and testing capacity, accuracy, and logistical challenges in Africa. <i>PanAfrican Medical Journal</i>. 39(89):Online. en
dc.publicationyear 2021 en
dc.contributor.author1 Mosi, L. en
dc.contributor.author2 Sylverken, A.A. en
dc.contributor.author3 Oyebola, K. en
dc.contributor.author4 Badu, K. en
dc.contributor.author5 Dukhi, N. en
dc.contributor.author6 Goonoo, N. en
dc.contributor.author7 Mante, P.K. en
dc.contributor.author8 Zahouli, J. en
dc.contributor.author9 Amankwaa, E.F. en
dc.contributor.author10 Tolba, M.F. en
dc.contributor.author11 Fagbamigbe, A.F. en
dc.contributor.author12 De Souza, D.K. en
dc.contributor.author13 Matoke-Muhia, D. en


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