Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk

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dc.date.accessioned 2012-03-28 en
dc.date.accessioned 2023-07-22T16:01:24Z
dc.date.available 2023-07-22T16:01:24Z
dc.date.issued 2015-08-25 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/3488
dc.description.abstract The prevalence of obesity has increased in societies of all socio-cultural backgrounds. To date, guidelines set forward to prevent obesity have universally emphasized optimal levels of physical activity. However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited. The Modeling the Epidemiologic Transition Study (METS) is a cohort study designed to assess the association between physical activity levels and relative weight, weight gain and diabetes and cardiovascular disease risk in five population-based samples at different stages of economic development. Twenty-five hundred young adults, ages 25-45, were enrolled in the study; 500 from sites in Ghana, South Africa, Seychelles, Jamaica and the United States. At baseline, physical activity levels were assessed using accelerometry and a questionnaire in all participants and by doubly labeled water in a subsample of 75 per site. We assessed dietary intake using two separate 24-hour recalls, body composition using bioelectrical impedance analysis, and health history, social and economic indicators by questionnaire. Blood pressure was measured and blood samples collected for measurement of lipids, glucose, insulin and adipokines. Full examination including physical activity using accelerometry, anthropometric data and fasting glucose will take place at 12 and 24 months. The distribution of the main variables and the associations between physical activity, independent of energy intake, glucose metabolism and anthropometric measures will be assessed using cross-section and longitudinal analysis within and between sites. METS will provide insight on the relative contribution of physical activity and diet to excess weight, age-related weight gain and incident glucose impairment in five populations? samples of young adults at different stages of economic development. These data should be useful for the development of empirically-based public health policy aimed at the prevention of obesity and associated chronic diseases. en
dc.format.medium Print en
dc.subject WEIGHT MANAGEMENT en
dc.subject FOOD AND NUTRITION en
dc.subject CHRONIC ILLNESS en
dc.subject HEALTH en
dc.title Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume 11 en
dc.BudgetYear 2011/12 en
dc.ResearchGroup Population Health, Health Systems and Innovation en
dc.SourceTitle BMC Public Health en
dc.ArchiveNumber 7192 en
dc.PageNumber Online en
dc.outputnumber 5839 en
dc.bibliographictitle Luke, A., Bovet, P., Forrester, T.E., Lambert, E.V., Plange-Rhule, J., Schoeller, D.A., Dugas, L.R., Durazo-Arvizu, R.A., Shoham, D., Cooper, R.S., Brage, S., Ekelund, U. & Steyn, N.P. (2011) Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk. BMC Public Health. 11:Online. http://hdl.handle.net/20.500.11910/3488 http://hdl.handle.net/20.500.11910/3488 en
dc.publicationyear 2011 en
dc.contributor.author1 Luke, A. en
dc.contributor.author2 Bovet, P. en
dc.contributor.author3 Forrester, T.E. en
dc.contributor.author4 Lambert, E.V. en
dc.contributor.author5 Plange-Rhule, J. en
dc.contributor.author6 Schoeller, D.A. en
dc.contributor.author7 Dugas, L.R. en
dc.contributor.author8 Durazo-Arvizu, R.A. en
dc.contributor.author9 Shoham, D. en
dc.contributor.author10 Cooper, R.S. en
dc.contributor.author11 Brage, S. en
dc.contributor.author12 Ekelund, U. en
dc.contributor.author13 Steyn, N.P. en


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