Self-report and dry blood spot measurement of antiretroviral medications as markers of adherence in pregnant women in rural South Africa

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dc.date.accessioned 2024-11-28T17:04:25Z
dc.date.available 2024-11-28T17:04:25Z
dc.date.issued 2017-04-04 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/10890
dc.description.abstract Antiretroviral (ARV) adherence is essential to prevent mother-to-child transmission of HIV. This study compared self-reported adherence versus ARV detection in dried blood spots (DBS) among N = 392 HIV-infected pregnantwomen in SouthAfrica (SA).Women completed two self-reported adherence measures [visual analog scale (VAS), AIDS Clinical Trials Group Adherence (ACTG)]. Adherence was 89% (VAS), 80% (ACTG), and 74% (DBS). Self-report measuresmarginally agreed withDBS(VAS:Kappa = 0.101, Area under the ROC curve (AUROC) = 0.543; ACTG: Kappa = 0.081,AUROC = 0.538). Self-reported adherence was overestimated and agreement with DBS was poor. Validation of self-reportedARVadherence among pregnant HIV women in SA is needed. en
dc.format.medium Print en
dc.subject HIV/AIDS en
dc.subject ANTIRETROVIRAL THERAPY (ART) en
dc.subject RURAL COMMUNITIES en
dc.subject PREGNANCY en
dc.title Self-report and dry blood spot measurement of antiretroviral medications as markers of adherence in pregnant women in rural South Africa en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume 21(7) en
dc.BudgetYear 2016/17 en
dc.ResearchGroup HIV/AIDS, STIs and TB en
dc.SourceTitle AIDS and Behavior en
dc.ArchiveNumber 9744 en
dc.PageNumber 2135-2140 en
dc.outputnumber 8636 en
dc.bibliographictitle Alcaide, M.L., Ramlagan, S., Rodriquez, V.J., Cook, R., Peltzer, K., Weiss, S.M., Sifunda, S. & Jones, D.L. (2017) Self-report and dry blood spot measurement of antiretroviral medications as markers of adherence in pregnant women in rural South Africa. AIDS and Behavior. 21(7):2135-2140. http://hdl.handle.net/20.500.11910/10890 http://hdl.handle.net/20.500.11910/10890 en
dc.publicationyear 2017 en
dc.contributor.author1 Alcaide, M.L. en
dc.contributor.author2 Ramlagan, S. en
dc.contributor.author3 Rodriquez, V.J. en
dc.contributor.author4 Cook, R. en
dc.contributor.author5 Peltzer, K. en
dc.contributor.author6 Weiss, S.M. en
dc.contributor.author7 Sifunda, S. en
dc.contributor.author8 Jones, D.L. en


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